The vehicle ploughed into the outside seating area of a restaurant in central Muenster at around 3:30 PM on Saturday. Reul said two people were killed in the crash, lowering the previous figure provided by police.
Police sources said that the incident is being treated as an intentional act, but details about a possible motive were not immediately known.
Ulrike Demmer, a German government spokesperson, tweeted that the crash was "terrible news". The driver shot and killed himself shortly after the incident. Another 20 were injured, six of them seriously, according to RAI public broadcaster.
A senior German security official briefed on the ongoing investigation said that investigators believe the attacker was the 48-year-old in whose name the van is registered and that he had recently tried to take his life.
Police spokesman Peter Nuessmeyer told the Associated Press that he could not confirm German media reports that the perpetrator reportedly had psychological issues.
Police block a street near a place where a vehicle drove into a group of people killing several and injured many in Muenster, Germany, on April 7, 2018. Saturday was the warmest day this year, with the temperature hitting 76 degrees in the city of 300,000, drawing people out to lounge in the sunshine.
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Joe Manchin, who is facing a tough re-election bid. "In case you take a look at your senator". Thousands and thousands and hundreds of thousands of individuals.
Authorities said they found a suspicious object in the vehicle, but they did not reveal what it was.
Merkel has allowed in more than one million asylum seekers in the past two years - a decision that has driven the rise of the far-right Alternative for Germany (AfD) party, which charges that the influx spells a heightened security risk.
"I heard a loud bang, screaming", Hur said. "There were lots of people", Simonsen said.
A local police spokesman Andreas Bode said German police had followed up on reports other potential suspects may have fled from the van following the crash.
Merkel said, "everything conceivable is being done to investigate the crime and to support the victims and their relatives". The hospital was forced to suspend its call for donors because so many people came forward.
Germany had long warned of the threat of more violence ahead after several attacks claimed by the Islamic State jihadist group, the bloodiest of which was a truck rampage through a Berlin Christmas market in December 2016 that left 12 people dead.