The death toll has drawn worldwide criticism, but the United States, which has drawn Arab anger by relocating its embassy to Jerusalem from Tel Aviv, has echoed Israel in accusing Gaza's ruling Hamas movement of instigating violence.
Lebanese Prime Minister Saad Hariri calls the USA decision to move its embassy to Jerusalem a "provocative" act that closes the doors for any attempts to reach peace between the Israel and Palestinians.
Trump, in a recorded message, said he remained committed to peace between Israel and the Palestinians.
The opening comes amid heightened tensions across the region.
Larijani's comments come almost a week after Trump pulled America out of the nuclear deal Iran struck with world powers in 2015.
In the Gaza Strip, tens of thousands of Palestinians are expected to march to the fence separating them from Israel, concluding seven weeks of confrontations with Israeli forces.
United States school shooting injures one; 14-year-old gunman in custody
Bureau of Alcohol, Tobacco, Firearms and Explosives officials also responded to the shooting, the agency tweeted. Nadine Luke told CNN her 18-year-old daughter called her, screaming, after she heard shots in the school.
Since weekly border marches began in late March, 42 Palestinian protesters have been killed and more than 1 800 wounded by Israeli army fire. The opening of the US Embassy there later tonight will bring together the Israeli and US leadership in a way we haven't seen before.
The ceremony moving the United States embassy in Israel from Tel Aviv to Jerusalem began with the USA national anthem.
Israel says the demonstrations are orchestrated by Hamas and has insisted its forces are acting "according to standard operating procedures". Additionally, police officers will stand in a "human wall" between the neighborhood of Arnona, where the new embassy is located, and the Palestinian Sur Baher, the police said.
A senior aide to Palestinian President Mahmoud Abbas has sharply criticized President Donald Trump over his decision to open a U.S. Embassy in contested Jerusalem, saying the American administration is "based on lies". "Today's move of the United States embassy gives life to a religious conflict instead of a dignified peace".
The ramifications could also be felt further afield: Turkish President Recep Tayyip Erdogan has threatened to cut diplomatic ties with the USA, while Saudi Arabia's King Salman has said that "such a unsafe step is likely to inflame the passions of Muslims around the world". Hundreds of Palestinians were treated for tear gas inhalation.
President Trump's decision past year to recognise Jerusalem as Israel's capital broke with decades of U.S neutrality on the issue, and put it at odds with most of the worldwide community.
Moore recently told the BBC: 'The Palestinians have referred to East Jerusalem to be the capital of a Palestinian state. The US has said the decision to relocate the embassy doesn't prejudge the final outcome of the city's status.
"Jerusalem must remain a city that brings people of all faiths together", Kushner, the United States envoy to the Middle East, will say at the opening.
But Guatemala plans to open an embassy in Jerusalem on Wednesday, and its ambassador visited the new site, in an office building in the western part of the city on Monday. Since the compound isn't large enough to host all the staff now based in Tel Aviv, Friedman and other officials will commute back and forth. However, they have not said how they will move forward without the Palestinians.