The 27-year-old has admitted that City's clash with Liverpool on Sunday will be the Citizens most hard challenge on the road this season.
However, if he gets his timing right there will be an opportunity for the Liverpool full back to exploit City's left flank with his impressive crossing from out wide.
The Brazilian keeper and his City team-mates are close with their Brazilian Liverpool counterparts, but with so much at stake in this fixture, they will revert to just Liverpool players for the duration of the game. As a player, you're looking to plant a seed in the opposition's heads that you're better than them in these big games.
Though his side have already lost three times to Liverpool in 2018 - conceding seven goals in their two trips to Anfield - he has maintained City won't park the bus. But last season we proved on a couple of occasions we are more than capable of going blow-to-blow with them and producing performances that deservedly win games against them.
The front three of Leroy Sane, Sergio Aguero and Raheem Sterling has worked very well in recent weeks, and while there's a possibility of Gabriel Jesus returning if Guardiola uses a 3-5-2, it would be odd for him to disturb the cohesion in that zone. "They are a top side and reached the Champions League final".
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Barca have wobbled domestically lately with two draws and a defeat, to bottom side Leganes, in their last three matches. We must play on Monday against City and then Wednesday or Thursday and then on Saturday again.
Despite reports of Guardiola punishing the 24-year-old for being late to training earlier this week, Mendy has complimented his boss on his progress with the Premier League champions. "That was that day, and they will try to strike back".
Salah still hasn't hit the heights of last season, although he has managed three goals.
"Obviously we won the last three games against City".
And Sky Sports pundit Neville says that he thinks it was a mistake to play all three forwards for nearly the full game against Napoli. Look at the game at Manchester City - there was an offside goal, which was not offside, which could have changed the game, but we were really calm. So you can understand why people might think they have City's number.
"You have to be ready, you need a fantastic football team - which thank God I have - with outstanding character, ready to be really fearless, ready to make mistakes".